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Although this metabolic pathway has been more extensively studied in tissues such as the liver, the unique high CYP1B1 environment in fibroid tissue suggests that local metabolism of E may constitute an intrinsic source of ROS [46]

doi: 10.1016/j.mehy.2013.11.013 307 BarzegariAKheyrolahzadehKHosseiniyan KhatibiSMSharifiSMemarMYZununi VahedS

At baseline, there was no significant difference in the Comp scores between groups ( P = 0.260)